There are several options available to couples to assist them with conception
when getting pregnant has eluded them. Talk to your personal physician
about specialists near you who can provide you with the fertility treatment that
suits your individual needs.
Ovulation Induction
Ovarian Induction, or OI, is used for women whose
periods are irregular or need enhanced progesterone production. Clomiphene
Citrate (Clomid or Serophene) is used in this treatment, binding to estrogen
receptor sites in the woman's brain - making the body think there is not enough
estrogen being produced. The hypothalamus then releases gonadotrohon-releasing
hormone, causing the pituitary gland to release more LH and FSH. The
woman's body then causes the follicle to begin maturing an egg.
About 80 percent of women using clomiphene become
successfully pregnant in the first three months of treatment. This rate
significantly drops after the first three months. Each month the woman
will take about five days of oral clomiphene, beginning with a 50 mg dose, often
between days 3-7 or 4-8. Some women will require treatment as late as days
5-9. Side effects may include headaches, nausea, weight gain, bloating,
hot flashes and breast tenderness. Treatment should not continue longer
than six months. Be sure to talk to your doctor about potential side
effects and dangers of ovulation induction before beginning treatment
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Intrauterine Insemination
Also known as artificial insemination, IUI
assists natural fertilization by bringing the sperm closer to the waiting egg.
It is often used when sperm quality is low, there are low numbers of anti-sperm
antibodies, cervical mucus is hostile or follicle-stimulating hormone levels are
high. After a woman ovulates, washed sperm in injected into the uterus
with a catheter through the cervix. Drugs may be used to begin ovulation,
with the procedure occurring within six hours of ovulation.
Success rates are about 10 percent each cycle if
used without drugs. If IUI is used with an HCG injection, success rates
move up to 15 percent. Be sure your doctor allows you at least thirty
minutes time to lay down following the procedure. Discomfort is minimal
with this procedure.
In Vitro Fertilization
IFV is used with couples who have tried other
fertilization methods unsuccessfully. Vitro means "in glass" - where your
egg is fertilized in a petri dish. Multiple follicles are cultivated so
several eggs can be harvested through surgical extraction. The eggs are
fertilized in the lab and placed back inside the uterus. The woman
receives hormone treatment during this time to make her body ready to receive an
embryo.
Side effects can include irritability, hot
flashes and other menopausal symptoms. IVF can take a toll on both you and
your family, as it takes time and can bring about lots of emotions. Costs
can reach over $55,000 for successful treatment - but to some, having a baby is
priceless.
Egg retrieval is usually carried out using a
vaginal ultrasound probe that guides a needle to aspirate each follicle.
Women are usually given a sedative for this procedure. Some clinics may
use a laparoscopic procedure that will require general anesthetic. The
hope is that eggs retrieved are of high quality, no matter what the count.
On the night of the procedure, the woman will begin taking progesterone by
suppository or injection.
Following egg retrieval, the male's sperm is
provided - usually in the clinic. It is washed and placed with the eggs in
a petri dish or test tube in the lab, which is incubated at 98.6 degrees
Fahrenheit. They are examined 18 hours later to determine if fertilization
has occurred. Within 48 hours, fertilized eggs will have begun cell
division and they will be ready to transfer back into the female.
Another form of fertilization is
intracytoplasmic sperm injection, or ICSI. One sperm is injected into an
egg with a fine glass needle. This procedure is used if the sperm has not
been capable of penetrating the egg naturally.
If you are at high risk for genetic disorders,
your fertilized eggs will be graded and genetic disorder testing is completed
before implantation. Transfer will occur from 48 hours to five days after
fertilization. The embryo is placed in a small catheter and is inserted
into the cervix and the uterus. It embryo is deposited at the top of your
uterus. It is important to relax as much as you can during this stage.
Stress can cause your uterus to contract, which will lower your chances for
implantation. You will not know if pregnancy is achieved for about two
weeks - a long and excruciating wait for most!